eBook: Bcl-xl

of human Bcl-xL. Antibodies are purified by protein A and. peptide affinity chromatography. ... Immunoprecipitation of Bcl-xL from Jurkat cell extracts, using ... [more...]

interacts with the Bcl2 family member Bcl-xl, which normally ... increased expression of ARF decreases Beclin-1/Bcl-xl com- plexes in cells, thereby providing a basis for ARF ... [more...]

bcl-2 and bcl-xL was studied by immunohistochemis- try in skin and bone marrow lesions of mastocytosis ... apoptotic proteins such as bcl-2 and bcl-xL that inhibit. apoptosis by ... [more...]

observed to Bcl-xL, inspite of its similarity insize, sequence, location and function to Bcl-2. The original ... developed using one of three epitope-specific anti-Bcl-xL ... [more...]

Abstract Changes in drug sensitivity in Bcl-XL small interfering RNA (siRNA) transfected Hepg2. hepatocellular carcinoma cells were investigated in this study. ... [more...]

molecule Bcl-xL linked by a 2A picornavirus self-cleaving peptide into CD4 ... T cells expressing both FoxP3 and Bcl-xL were able to differentiate into functional Tregs, ... [more...]

The aim of our study was an evaluation of Bcl-xl and Bak. protein expressions in optic nerve axons in eyeballs ... the injured eyeballs in Group I, Bcl-xl protein expression was ... [more...]

Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) ... overexpressing antiapoptotic proteins such as Bcl-XL or Ku70. ... [more...]

Application of recombinant BCL-xL through a patch pipette to mitochondria ... of full-length BCL-xL protein into the presynaptic terminal enhanced ... [more...]

A role for BCL-xL in regulating neuronal activity is suggested by its dramatic effects on ... to explore the role of endogenous BCL-xL in synaptic function. ... [more...]

homologue Bcl-xL, are both resistant to the anti-apoptotic effect of Bcl-2. This ... This murine hybridoma expresses low levels of Bcl-xL and is highly sensitive to ... [more...]

Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it ... [more...]

Bcl-xL is a member of the Bcl-2 family of. proteins that are critical regulators of ... 4. Gonzalez-Garcia M, Perez-Ballestro R, Ding L et al. bcl-xL ... [more...]

Abstract Bcl-XL is overexpressed in a variety of human tumors and is involved in tumorigenesis and ... Expression levels of Bcl-XL mRNA and protein in siRNA stable ... [more...]

β1 production up-regulates Bcl-xL expression in normal. megakaryocytopoiesis, and that ... gate whether the progressive increase in the Bcl-xL expression ... [more...]

responsive element in the BCL-xL promoter (-865 to -847) by reporter gene assay, ... and the observation that BCL-xL is a key molecule. underlying hypoxia ... [more...]

Bcl-xL is a well characterized death-suppressing molecule of ... Bcl-xL is expressed in embryonic and adult. neurons of the CNS and may play a critical role in preventing ... [more...]

Background: Bcl-xL prevents apoptosis through two dif- ferent mechanisms: by ... embedded human lung carcinoma using Bcl-xL Antibody #2762 in the presence of ... [more...]

Bcl-xL is an anti-apoptotic mitochondrial protein. related to Bcl-w and the major transcript of the bcl-x gene ... This polyclonal antibody can be used for detection of Bcl ... [more...]

Target Information: Bcl-XL belongs to anti-apoptotic family members ... and Weintraub,S.J. Bcl-xL deamidation is a critical switch in the regulation of the ... [more...]

Histone Deacetylase Inhibitor Downregulation of bcl-xl Gene Expression ... totic protein BCL-XL, but not BCL-2, rendering bcl-xl gene. expression a potential ... [more...]

Bcl-xL is highly expressed in several types of cancers, and ... hypothesized that modulation of the Bcl-xL/ Bcl-xS ratio by regulating alternative ... [more...]

Bcl-xL is structurally related to the Bcl-2 gene. and is a member of the Bcl-2 family of ... Bcl-2 members is believed to promote cell. survival; its ratio to ... [more...]

We previously reported the Bcl-2/Bcl-xL-bispecific activity of the 2 ... the functional comparison of isosequential Bcl-2/Bcl-xL-bispecific 2 -MOE and LNA-modified anti ... [more...]

overexpressing Ramos cells, Ramos hemagglutinin (HA)-Bcl-x, which were not sensitized by ... activates expression of the apoptosis inhibitor Bcl-xl. ... [more...]

Significance of Bcl-xL in human colon carcinoma. You-Li Zhang, Li-Qun Pang, Ying Wu, Xiao ... HT29 was transfected with Bcl-xL small interfering RNA (siRNA), the ... [more...]

from human BCL-XL around the phosphorylation site of serine 62. ... BCL-XL (Ab-62) antibody detects endogenous levels of total BCL-XL protein. ... [more...]

Overexpression of Bcl-xL, an anti-apoptotic member. of the Bcl-2 family, negatively ... levels of Bcl-xL correlated with decreased cellular sensitivity ... [more...]

The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal ... dilution versus mouse antihuman Bcl-xL antibody (Santa Cruz Biotechnol ... [more...]