eBook: Bcl-2

cell death, with Bcl-2 gene products either enhancing. or diminishing the likelihood of ... with Bcl-2 after fluid percussion trauma significantly. improved ... [more...]

Bcl-2 initiates a new gene family involved in the regulation of cell death ... Overexpression of Bcl-2 on the other hand protects cells from death, but ... [more...]

This process is controlled by the BCL-2 family, which is composed of both pro- and anti ... BCL-2 effector proteins: The proteins BAX and BAK are the pro-apoptotic ... [more...]

We found that following BSO, U937 up-regulate Bcl-2 mRNA and protein levels, by a ... BSO-dependent Bcl-2 up-regulation is associated with the ability to survive to BSO. ... [more...]

assessed a potential protective effect of Bcl-2 on patholog ... the human bcl-2 transgene under the control of the neuron- specific enolase promoter was ... [more...]

In the present study, expressions of bcl-2, c-myc protein and reduced glutathione levels were evaluated ... Expression of bcl-2 protein, in tumor and its adjoining tissue of ... [more...]

Proapoptotic Bcl-2 Protein Capable of Dimerization with Diverse Antiapoptotic. BOD (Bcl-2-Related Ovarian Death Gene) Is an Ovarian BH3 Domain-Containing ... [more...]

apoptotic protein Bcl-2 from its proapoptotic relatives, little is known ... Bcl-2-IP3 receptor interaction prevents these BH4-mediated effects. ... [more...]

apoptotic protein, Bcl-2, promotes the survival of many types of neurons during development and in response ... whether Bcl-2 might similarly control cell death in sexually ... [more...]

The Bcl-2 family of pro-apoptotic and anti-apoptotic. proteins are important upstream ... Bcl-2 in transgenic mice prevents afferent depriva- tion-induced cell ... [more...]

The Bcl-2 family of proteins regulate, in part, the release of mitochondrial apoptogenic ... the BH3 domain of Bcl-2 enhance bortezomib-induced. apoptosis, whereas ... [more...]

pression of the antiapoptotic B-cell CLL/lymphoma 2 (BCL-2) protein. ... The Bcl-2-expressing system was previously described and was a gift from ... [more...]

ument Bcl-2-IP3R interaction within cells by FRET. and identify a Bcl-2 interacting region ... the IP3R and reversed Bcl-2-mediated inhibition of. IP3R channel ... [more...]

on its similarity with other Bcl-2 family proteins and energy minimization suggests the ... Members of the Bcl-2 family of proteins are key regulators of the ... [more...]

Here we investigate the function of zebrafish Bcl-2 family proteins and demonstrate important conservation of function across. zebrafish and mammalian systems. ... [more...]

Immunohistochemical Analysis of Bcl-2, Bax, and Bak Expression in Thyroid Glands ... clarify a role of apoptosis and the expression of Bcl-2 family proteins ... [more...]

bcl-2 and bcl-xL was studied by immunohistochemis- try in skin and bone marrow lesions of mastocytosis ... apoptotic proteins such as bcl-2 and bcl-xL that inhibit. apoptosis by ... [more...]

Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit ... cells (MCF-7B) reduced Bcl-2 protein levels while. increasing cell–cell adhesion, and ... [more...]

between bcl-2 and CD38 or ZAP-70 expression remains uncertain and was investigated using flow cytometric ... CLL cells were consistently bcl-2 positive but varied in expression ... [more...]

Bcl-2, a protein that blocks apoptosis by inhibiting the mitochondrial permeability transition ... cells that overexpress Bcl-2 compared with neomycin vector control ... [more...]

Bcl-2, Bcl-xL or Mcl-1 that display all four Bcl-2 homology ... Anti-apoptotic Bcl-2 family members localize at the. mitochondria, where they can prevent ... [more...]

Mitotic Chromosomal Bcl-2: II. Localization to Interphase Nuclei ... tion of bcl-2 during interphase, the point at which it is undetectable by immunofluo ... [more...]

Bcl-2 plays in regulating the survival of specific motor neuron populations. ... sensitivity to bcl-2 deletion may exist within branchiomotor. neurons of the facial ... [more...]

When Bcl-2 transgenic DC were used as DC vaccines, they induced 2- to ... Overall, these data indicate that down-regulation of Bcl-2 controls DC longevity, which in ... [more...]

Proteins in the Bcl-2 family are central regulators of programmed ... and Bcl-2, are overexpressed in many cancers and contribute to. tumour initiation, ... [more...]

Significance of Bcl-2 and Bax proteins in cervical carcinogenesis: ... immunohistochemically studied for involvement of Bcl-2 and Bax proteins in cervical ... [more...]

related to MCL-1 than to BCL-2, a result confirmed by sequence analysis. ... We found that both BCL-2 and BHRF-1 sequestered pro-death BH3-only proteins under growth ... [more...]

Phylogenomics of Life-Or-Death Switches in Multicellular Animals: Bcl-2, ... ered as adenoviral E1B 19K/Bcl-2 interacting proteins and. then classified into this ... [more...]